Central and peripheral demyelination

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منابع مشابه

Combined Central and Peripheral Demyelination.

Demyelinating disorders are very common, but remains isolated to the part of nervous system they involve. However, infrequently, combined involvement of central and peripheral nervous system with demyelinating process have been described. We report one such rare case, with possible theories of common etiological basis. We present a middle aged male patient with Chronic Inflammatory Demyelinatin...

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Chemokines and peripheral nerve demyelination.

It has been speculated that beta-chemokines play a pivotal role in the development of peripheral nervous system (PNS) disorders characterized by mononuclear cell infiltration. In experimental allergic neuritis (EAN), an animal model for human Guillain-Barré syndrome (GBS) with mononuclear cell infiltration, we found by quantitative PCR that beta-chemokine messages were upregulated during the ac...

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Anti-neurofascin antibody in patients with combined central and peripheral demyelination.

OBJECTIVES We aimed to identify the target antigens for combined central and peripheral demyelination (CCPD). METHODS We screened target antigens by immunohistochemistry and immunoblotting using peripheral nerve tissues to identify target antigens recognized by serum antibodies from selected CCPD and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) cases. We then measured the ...

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Acute combined central and peripheral demyelination showing anti-aquaporin 4 antibody positivity.

Neuromyelitis optica spectrum disorder (NMOSD) is characterized by optic neuritis or transverse myelitis with anti-aquaporin 4 (AQP4) antibodies (1). We herein present the case of a patient with NMOSD who also was affected with peripheral neuropathy. A 58-year-old woman developed gait disturbance and sensory impairment in the lower limbs. She exhibited longitudinally extensive transverse myelit...

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Abnormal evoked potentials in Miller-Fisher syndrome: further evidence of combined peripheral and central demyelination.

1 Tsuji I, Nakajima F, Morimoto J, Nounaka Y. The sexual function in patients with spinal cord injury. Urol Int 196 1;12:270-80. 2 Brindley GS. The actions of parasympathetic and sympathetic nerves in human micturition, erection and seminal emission and their restoration in paraplegic patients by implanted electrical stimulators. Proc R Soc Lond 1988;B235: 111-20. 3 Yeates WK. Ejaculation and i...

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ژورنال

عنوان ژورنال: Journal of Neurosciences in Rural Practice

سال: 2014

ISSN: 0976-3147,0976-3155

DOI: 10.4103/0976-3147.127887